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WHO expects additional cases of MERS-CoV infection in M.East

WHO expects additional cases of MERS-CoV infection in M.East

Baku, July 26, AZERTAC

On 10 July 2023, the United Arab Emirates (UAE), notified WHO of a case of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) in a 28-year-old male from Al Ain city in Abu Dhabi. The case had no history of direct or indirect contact with dromedaries, goats, or sheep. The patient was admitted to the hospital on 8 June, according to the official website of the organization.

A nasopharyngeal swab was collected on 21 June and tested positive for MERS-CoV by polymerase chain reaction (PCR) on 23 June 2023. All 108 identified contacts were monitored for 14 days from the last date of exposure to the MERS-CoV patient. No secondary cases have been detected to date.

Since July 2013, when the UAE reported the first case of MERS-CoV, 94 confirmed cases (including this new case) and 12 deaths have been reported. Globally, the total number of confirmed MERS-CoV cases reported to WHO since 2012 is 2605, including 936 associated deaths.

WHO continues to monitor the epidemiological situation and conducts risk assessments based on the latest available information. WHO expects that additional cases of MERS-CoV infection will be reported from the Middle East and/or other countries where MERS-CoV is circulating in dromedaries.

WHO re-emphasizes the importance of strong surveillance by all Member States for acute respiratory infections, including MERS-CoV, and to carefully review any unusual patterns.

On 10 July 2023, the International Health Regulations National Focal Point (IHR NFP) of the United Arab Emirates (UAE) notified WHO of a confirmed case of MERS-CoV in Abu Dhabi. The patient is a 28-year-old male, non- Emirati national living in Al Ain city, a non-healthcare worker. The case visited a private medical center multiple times between 3 and 7 June 2023, complaining of vomiting, right flank pain, and dysuria (pain when passing urine). On 8 June, the case presented to a government hospital with vomiting, and gastrointestinal symptoms including diarrhea, and was given an initial diagnosis of acute pancreatitis, acute kidney injury, and sepsis.

On 13 June, he was in critical condition and referred to an intensive care unit (ICU) at a specialized government tertiary hospital where he was put on mechanical ventilation. He deteriorated and a nasopharyngeal swab was collected on 21 June and tested positive for MERS-CoV by PCR on 23 June 2023.

The case has no known co-morbidities, no history of contact with MERS-CoV human cases, and no recent travel outside the UAE. The patient has no known history of direct contact with animals including dromedary camels, nor consumption of their raw products.

All 108 contacts that were identified have been monitored for 14 days from the last date of exposure to the MERS-CoV patient, no secondary case was identified. The case has no family members or household contacts identified in the UAE.

Prior to this notification, the last MERS-CoV infection reported from the UAE was in November 2021. The first laboratory-confirmed case of MERS-CoV in UAE was in July 2013. Since then, the UAE has reported 94 cases of MERS-CoV (including this current case) and 12 associated deaths (Case Fatality Ratio (CFR): 13%). Humans are infected with MERS-CoV from direct or indirect contact with dromedaries, a host and zoonotic source of MERS-CoV infection. MERS-CoV has demonstrated the ability to be transmitted between humans. So far, the observed non-sustained human-to-human transmission has occurred among close contacts and in healthcare settings. Outside of the healthcare setting, there has been limited human-to-human transmission.

Cases of MERS-CoV infection are rare in the UAE. Since July 2013, a total of 94 MERS-CoV cases, including this current case, resulting in 12 deaths (CFR 13%) have been reported to WHO from the UAE.

The notification of this case does not change the overall risk assessment. WHO expects that additional cases of MERS-CoV infection will be reported from the Middle East and/or other countries where MERS-CoV is circulating in dromedaries, and that cases will continue to be exported to other countries by individuals who were exposed to the virus through contact with dromedaries or their products (for example, consumption of camel’s raw milk), or in a healthcare setting.

WHO continues to monitor the epidemiological situation and conducts risk assessments based on the latest available information.

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