Scientists have discovered why smokers lose weight
Baku, June 11 (AZERTAC). A team of American scientists from Yale Medical School has found that nicotine not only causes human relationship, but also gives the false body chemical signals of satiety, says the magazine Science.
Scientists hope that these data will help in creating new drugs to fight obesity.
As statistics show, the body weight of smokers is on average lower than non-smokers. In addition to the pleasure centers, nicotine acts on the acetylcholine receptors in the central nervous system that regulate feeding behavior of the individual. Nicotine suppresses the appetite not only humans but also animals - mice, whose food was administered a small amount of this substance, they ate twice as less than animals in the control group.
In the study, led by Marina Pichchiotto scientists have studied the action of nicotine on the brain satiety center of the mouse and found that loss of appetite in animals is not associated with addiction, which causes nicotine.
Scientists compared the effects of nicotine on the nervous system and its analogue cytisine, which is not addictive. And he and other drug significantly reduces appetite in laboratory. If the animals were injected mekamilamin - nicotine antagonist compound that blocks its action on the central nervous system, appetite was restored. Scientists note that other similar compound antagonist - geksametony do not penetrate into the tissues of the CNS, is not restored appetite, depressed by nicotine.
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