New transplant technique breathes life into lungs
Baku, December 16 (AZERTAC). New York Presbyterian Hospital Presbyterian Hospital published a revolutionary technique in transplant. Thanks to it, more patients will be able to get lungs suitable for transplantation, according to ABC News.
The technique, called "ex vivo" -- or, outside the body -- involves taking the lungs that were removed from the donor and placing them in a transparent case, where they are hooked up to a pump and ventilator. The lungs are closely monitored for up to four hours as they are nourished with nutrients and antibiotics and pumped with oxygen.
Doctors keep a donated lung "breathing" until it can be transplanted into a recipient in need. In the traditional lung-transplant approach, the lungs are assessed in the deceased donor’s body before being removed. If the lung is considered viable, it is stored in cold temperatures within a short window of time before the transplant.
But the new preservation technique "revives" the lungs in a transparent box by gradually warming the lungs to normal body temperature, and the organ is reinstated in an environment as if it is in the body. The lungs are assessed and reconditioned in the operating room until the final minute before being placed in the recipient’s body.
"It allows us to get a better judgment of the organ," said Block’s surgeon, Dr. Frank D’Ovidio, associate surgical director of the lung transplant program at New York-Presbyterian/Columbia University Medical Center.
Nearly 30 percent of donor lungs are unsuitable for transplantation. But is some cases, otherwise viable lungs might be deemed inappropriate for transplant because the tests might not be accurate, D’Ovidio said.
In 2011, nearly 1,400 lung transplants were performed, according to the Organ Procurement and Transplantation Network, part of the U.S. Department of Health and Human Services.
“We have the potential to increase, even double, the number of transplants we’re performing, and to satisfy the needs for more lung transplants," D’Ovidio said.
Bloch is one of 25 patients enrolled in a three-year FDA clinical trial involving five medical centers across the nation. The trial is designed to compare the ex vivo approach to the traditional method, and will be reviewed by the FDA to assess whether the technique is safe and should be cleared for standard use.
"We used lungs we would’ve not been able to do otherwise," D’Ovidio said. "Initial tests proved concerns, but instead, we tested over time ex vivo and we saw improvement in the lung."
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